Fig. 4
From: How to use CT texture analysis for prognostication of non-small cell lung cancer

Left lower lobe NSCLC showing cavitation and adjacent consolidation. The fused FDG-PET/CT image (a) and narrow CT windows (b) can assist identification of the tumour margins. Using automatic segmentation, the initial manually constructed ROI (b) includes adjacent lung and the area of cavitation but excludes the adjacent mediastinal structures and pulmonary consolidation. The final ROI defined by the automated segmentation procedure (c) exlcudes the adjacent lung and area of cavitation. The final filtered tumour image is shown in (d)