Table 1 Comparison between quantitative parameters achieved from OSEM and Q.Clear reconstructed images
OSEM Recon | Q.Clear Recon | |
|---|---|---|
Target lesion | ||
Prostate gland/Prostate bed | 3 (6) | 3 (6) |
Lymph nodes | 6 (12) | 7 (14) |
Bone | 40 (80) | 39 (78) |
Viscera | 1 (2) | 1 (2) |
Disease volume | ||
Low (MTV < 40 mL) | 11 (22) | 11 (22) |
High (MTV > 40 mL) | 39 (78) | 39 (78) |
Total population | ||
SUVmax (range) | 38.7 (4.1–133.3) | 47.1 (4.4–180.4) |
Mean difference (95% CI) | 8.4 (5.2–11.5) | |
SUVmean (range) | 7.1 (3.3–13.0) | 7.8 (3.3–14.8) |
Mean difference (95% CI) | 0.7 (0.5–0.9) | |
MTV (range) | 654.5 (2.8–4552.8) | 632.9 (2.9–4833.9) |
Mean difference (95% CI) | -21.5 (-48.2–26.7) | |
Low volume disease (MTV < 40 ml) | ||
SUVmax (range) | 19.8 (4.1–44.5) | 23.8 (4.4–63.4) |
Mean difference (95% CI) | 4.0 (0.4–7.7) | |
SUVmean (range) | 6.0 (3.3–10.3) | 6.6 (3.3–11.8) |
Mean difference (95% CI) | 0.6 (0.2–1.1) | |
MTV (range) | 15.0 (2.8–24.4) | 14.6 (2.9–27.7) |
Mean difference (95% CI) | -0.4 (-2.0–1.3) | |
High volume disease (MTV > 40 ml) | ||
SUVmax (range) | 44.1 (9.43–133.3) | 53.7 (8.0–180.4) |
Mean difference (95% CI) | 9.6 (5.7–13.5) | |
SUVmean (range) | 7.4 (4.2–13) | 8.1 (4.22–14.8) |
Mean difference (95% CI) | 0.7 (0.5–0.9) | |
MTV (range) | 834.8 (49–4552.8) | 807.3 (48.2–4833.9) |
Mean difference (95% CI) | -27.5 (-61.8–6.8) | |
SUVmean threshold subgroup analysis | ||
SUVmean < 10 | 39 (78) | 37 (74) |
SUVmean ≥ 10 | 11 (22) | 13 (26) |
SUVmean < 7 | 25 (50) | 24 (48) |
SUVmean ≥ 7 | 25 (50) | 26 (52) |