Table 1 Association between Clinical features and EGFR mutation status
Characteristic | Total | EGFR (+) | EGFR (-) | P value |
|---|---|---|---|---|
No. of patients | 109 | 22 (20.18) | 87 (79.82) | |
Sex | ||||
Male | 83 (76.15) | 8 (36.36) | 75 (86.21) | < 0.001 |
Female | 26 (23.85) | 14 (63.64) | 12 (13.79) | |
Age (y)a | 66.07 ± 8.14 | 64.82 ± 7.04 | 66.39 ± 8.41 | 0.421 |
Smoking history | < 0.001 | |||
Never a smoker | 37 (33.94) | 15 (68.18) | 22 (25.29) | |
Smoker | 72 (66.06) | 7 (31.82) | 65 (74.71) | |
Smoking amount (pack-year)b | 25(0,45) | 0(0,25) | 30(0,45) | 0.007 |
Histologic finding | 0.007 | |||
Adenocarcinoma | 78 (71.56) | 21 (95.45) | 57 (65.52) | |
Squamous cell carcinoma | 27 (24.77) | 1 (4.55) | 26 (29.88) | |
Others | 4 (3.67) | 0 (0) | 4 (4.60) | |
TNM staging | 0.034 | |||
I + II | 21(19.27) | 8 (36.36) | 13 (14.94) | |
III + IV | 88 (80.73) | 14 (63.64) | 74 (85.06) | |
Diagnostic technique | ||||
Surgery | 24 (22.02) | 11 (50) | 13 (14.94) | |
CT-guided biopsy | 82 (75.23) | 11 (50) | 71 (81.61) | |
others | 3 (2.75) | 0 (0) | 3 (3.45) |