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Table 3 Comparisons of ADC and DKI histogram metrics obtained by using whole tumor analysis

From: Histogram analysis of multiple diffusion models for predicting advanced non-small cell lung cancer response to chemoimmunotherapy

Parameters

ADC

 

P

Dk

 

P

K

 

P

Responders

(n = 41)

Non-responders

(n = 31)

 

Responders

(n = 41)

Non-responders

(n = 31)

 

Responders

(n = 41)

Non-responders

(n = 31)

 

10th

0.92 ± 0.12

0.96 ± 0.16

0.258

0.89 ± 0.15

0.93 ± 0.11

0.271

0.46 ± 0.14

0.42 ± 0.13

0.219

25th

1.12 ± 0.15

1.16 ± 0.20

0.299

1.11 ± 0.17

1.16 ± 0.14

0.195

0.72 ± 0.18

0.67 ± 0.18

0.200

75th

1.62 ± 0.22

1.75 ± 0.25

0.017

1.69 ± 0.18

1.77 ± 0.15

0.039

1.25 ± 0.29

1.14 ± 0.32

0.169

90th

1.89 ± 0.18

1.99 ± 0.24

0.053

1.93 ± 0.19

2.02 ± 0.15

0.038

1.45 ± 0.35

1.38 ± 0.41

0.446

Mean

1.40 ± 0.19

1.57 ± 0.25

0.001

1.45 ± 0.15

1.52 ± 0.13

0.032

0.98 ± 0.22

0.91 ± 0.24

0.216

Median

1.35 ± 0.22

1.47 ± 0.25

0.025

1.42 ± 0.17

1.49 ± 0.17

0.064

1.00 ± 0.24

0.91 ± 0.25

0.124

Skewness

1.55 ± 1.50

1.98 ± 2.14

0.258

0.41 ± 0.83

0.56 ± 0.96

0.484

-0.09 ± 0.68

0.24 ± 0.86

0.063

kurtosis

1.95 ± 2.23

3.01 ± 2.76

0.071

-0.05 ± 1.07

0.11 ± 1.26

0.838

0.51 ± 2.51

1.08 ± 2.10

0.055

Entropy

2.07 ± 1.06

2.30 ± 1.11

0.178

3.45 ± 0.23

3.54 ± 0.27

0.142

4.00 ± 0.25

3.92 ± 0.28

0.213