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Table 2 Cox proportional hazard model for the 5-year recurrence-free survival in 564 patients

From: CTR > 0.7 predicts the subgroup of lung adenocarcinomas ≤ 2 cm at risk of poor outcome treated by sublobar resection compared to lobar resection

Variate

Univariate

Multivariate

HR (95%CI)

P value

HR (95%CI)

P value1

Gender(Female)

0.273(0.129, 0.576)

0.001

0.5(0.234, 1.066)

0.073

Age(>56 years)

6.171(2.377, 16.026)

<0.001

3.850(1.442, 10.273)

0.007

Maximum tumor size(D>1 cm)

2.773(0.973, 7.906)

0.056

1.130(0.186, 6.883)

0.895

Consolidation component size(D>1 cm)

11.382(4.684, 27.656)

<0.001

0.962(0.187, 4.938)

0.963

CTR(CTR≥0.75)

74.969(10.233, 549.218)

<0.001

82.952(8.732, 788.019)

<0.001

Surgical approach(Sublobar resection)

1.502(0.734, 3.073)

0.265

3.612(1.750, 7.453)

0.001

  1. 1P Value determined by COX proportional hazard model. CI: confidence interval; CTR: consolidation tumor ratio; D: diameter; HR: hazard ratio