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Table 4 Cox proportional hazard regression of risk factors for tumor-progression with pulmonary-vascular-stump filling defect

From: The pulmonary-vascular-stump filling defect on CT post lung tumor resection: a predictor of cancer progression

 

Univariable Cox proportional hazard regression

Multivariable Cox proportional hazard regression(early onset)

Multivariable Cox proportional hazard regression(follow-ups)

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

Gender:

      

 Male

Reference

  

 Female

1.92 (0.85–4.36)

0.137

    

Age, years:

      

 ≤ 64

Reference

  

 >64

0.86 (0.41–1.8)

0.692

    

Histological types:

      

 Non-small cell

Reference

 

Reference

 

Reference

 

 Small cell

1.3(0.41–4.54)

0.610

0.71(0.42–0.83)

0.400

1.27(0.38–4.30)

0.696

Stage of cancer at surgery:

      

 Stage I/II

Reference

Reference

Reference

 Stage III/IV

2 (0.96–4.17)

0.070

1.18(0.38–1.55)

0.120

0.81(0.38–1.75)

0.592

Surgical intervention:

      

 Right side

Reference

  

 Left side

0.75 (0.36–1.56)

0.439

    

Location:

      

 Pulmonary artery stump

Reference

  

 Pulmonary vein stump

0.50 (0.17–1.43)

0.200

    

Shape:

      

 Convex shape

Reference

 

Reference

 

Reference

 

 Concave shape

0.43 (0.21–0.91)

0.026

0.46(0.39–1.99)

0.040

0.46(0.39–1.99)

0.757

Attenuation(Hounsfield unit)

      

 ≤ 38

Reference

     

 >38

1.52 (0.69–3.35)

0.295

    

Findings at follow-up:

      

 Stabilization or regression

Reference

  

 Increased

5.8 (2.67–12.62)

< 0.001

  

0.26(0.11–0.65)

0.004