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Table 1 Patient’s clinical and biological characteristics

From: DCE-MRI to distinguish all monoclonal plasma cell disease stages and correlation with diffusion-weighted MRI/PET-based biomarkers in a hybrid simultaneous whole body-2-[18F]FDG-PET/MRI imaging approach

Variable

Symptomatic MM

n = 67

SMM

n = 62

MGUS

n = 38

Mean age ± SD

64.2 ± (9.9)

66 ± (12.5)

61.8 ± (10.6)

Male

25/67 (37%)

24/62 (39%)

17/38 (45%)

R-ISS I

26/67 (39%)

N/A

N/A

R-ISS II

23/67 (34%)

N/A

N/A

R-ISS III

18/67 (27%)

N/A

N/A

Type of monoclonal Ig or free lights chains

 IgGκ

18/67 (27%)

23/62 (37%)

14/38 (37%)

 IgGλ

7/67 (10%)

19/62 (31%)

9/38 (24%)

 Κ

12/67 (18%)

4/62 (6%)

2/38 (5%)

 IgAλ

9/67 (13%)

3/62 (5%)

5/38 (13%)

 Λ

8/67 (12%)

3/62 (5%)

4/38 (10.5%)

 IgAκ

13/67 (20%)

10/62 (16%)

4/38 (10.5%)

 Mean serum monoclonal Ig (g/L) ± SD

28.6 ± (19.5)

23.2 ± (15)

11.5 ± (8.6)

 Mean bone marrow plasma cells (%) ± SD

28 ± (25)

17 ± (15)

4 ± (2.85)

  1. MM multiple myeloma, R-ISS revised international staging system, N/A not applicable, SD standard deviation