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Fig. 6 | Cancer Imaging

Fig. 6

From: Personalized prediction of immunotherapy response in lung cancer patients using advanced radiomics and deep learning

Fig. 6

Representative cases for the IO outcome prediction. The outcome of IO treatment is associated with the characteristics of the peritumoral vasculature and the physical properties of the tumor as observed on CT images. In two cases with similar tumor size, Case 1 (a), with a poorer prognosis, exhibited higher local heterogeneity of the tumor and curvature and tortuosity of the peritumoral vessels compared to Case 2 (b), with a better prognosis. Case 1 (a) also showed growth primarily in the area near the chest wall, with limited distribution of blood vessels around the tumor. These findings suggest that the effects of IO treatment and drug delivery may be influenced by these factors

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