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Table 2 Comparison of the spectral CT analysis results for lung cancer

From: Differentiation of pathological subtypes and Ki-67 and TTF-1 expression by dual-energy CT (DECT) volumetric quantitative analysis in non-small cell lung cancer

parameter

Volumetric spectral analysis

Conventional spectral analysis

ADC (n = 84)

SQCC (n = 35)

P value

ADC (n = 84)

SQCC (n = 35)

P value

Arterial Phase

      

 CT40-keV (HU)

135.14 ± 35.58

121.97 ± 29.73

0.056

134.43 ± 33.69

120.25 ± 33.52

0.058

 CT60-keV (HU)

71.15 ± 15.07

68.61 ± 12.50

0.382

71.73 ± 14.05

68.56 ± 14.64

0.270

 CT70-keV (HU)

55.99 ± 10.98

55.98 ± 8.86

0.998

56.89 ± 10.34

56.36 ± 10.77

0.801

 CT80-keV (HU)

46.30 ± 9.02

47.91 ± 6.94

0.347

47.41 ± 8.76

48.53 ± 8.79

0.526

 CT100-keV (HU)

35.42 ± 7.95

38.83 ± 5.63

0.009

36.74 ± 8.19

39.73 ± 7.47

0.065

 CT120-keV (HU)

30.16 ± 8.03

34.47 ± 5.55

0.001

31.60 ± 8.50

35.52 ± 7.33

0.019

 CT140-keV (HU)

27.00 ± 8.25

31.81 ± 5.66

<0.001

28.59 ± 8.50

32.93 ± 7.42

0.010

 K40–70

2.64 ± 0.90

2.20 ± 0.74

0.012

2.58 ± 0.88

2.13 ± 0.83

0.010

 K40–100

1.66 ± 0.57

1.39 ± 0.47

0.012

1.63 ± 0.55

1.34 ± 0.52

0.010

 Zeff

8.43 ± 0.27

8.29 ± 0.23

0.010

8.43 ± 0.26

8.29 ± 0.25

0.008

 IC (mg/cm3)

13.69 ± 4.82

11.36 ± 3.95

0.013

13.74 ± 4.66

11.31 ± 4.37

0.009

 NIC

0.15 ± 0.06

0.12 ± 0.05

0.009*

0.15 ± 0.06

0.12 ± 0.06

0.002*

 WC (mg/cm3)

1018.95 ± 9.37

1024.31 ± 6.27

0.001*

1021.18 ± 10.02

1026.30 ± 7.56

0.004*

Venous Phase

      

 CT40-keV (HU)

159.03 ± 37.94

156.82 ± 33.12

0.764

159.43 ± 36.49

153.15 ± 38.07

0.400

 CT60-keV (HU)

82.52 ± 16.75

84.72 ± 14.30

0.499

83.96 ± 16.60

83.79 ± 16.04

0.959

 CT70-keV (HU)

64.52 ± 12.65

67.74 ± 10.04

0.183

66.05 ± 12.63

67.09 ± 11.47

0.675

 CT80-keV (HU)

53.00 ± 10.49

56.85 ± 7.88

0.053

54.69 ± 10.52

56.47 ± 8.99

0.382

 CT100-keV (HU)

40.08 ± 8.88

44.61 ± 6.34

0.002

41.80 ± 9.17

44.50 ± 7.09

0.123

 CT120-keV (HU)

33.82 ± 8.55

38.70 ± 6.17

0.001*

35.59 ± 8.94

38.72 ± 6.77

0.041

 CT140-keV (HU)

29.95 ± 8.70

34.91 ± 6.86

0.001*

31.89 ± 8.97

35.25 ± 6.80

0.049

 K40–70

3.15 ± 0.92

2.97 ± 0.82

0.315

3.11 ± 0.88

2.87 ± 0.95

0.181

 K40–100

1.98 ± 0.57

1.87 ± 0.52

0.319

1.96 ± 0.56

1.81 ± 0.59

0.191

 Zeff

8.57 ± 0.26

8.52 ± 0.24

0.314

8.59 ± 0.26

8.52 ± 0.27

0.216

 IC (mg/cm3)

16.33 ± 4.68

15.40 ± 4.35

0.316

16.55 ± 4.69

15.30 ± 4.95

0.196

 NIC

0.42 ± 0.13

0.36 ± 0.08

0.006

0.43 ± 0.13

0.36 ± 0.09

0.009

 WC (mg/cm3)

1020.74 ± 9.04

1025.40 ± 6.92

0.002*

1023.29 ± 9.40

1026.47 ± 7.11

0.047

 ECV

0.25 ± 0.08

0.23 ± 0.06

0.047*

0.26 ± 0.08

0.23 ± 0.06

0.036

AEF

0.85 ± 0.18

0.75 ± 0.21

0.010

0.84 ± 0.17

0.75 ± 0.22

0.002*

NAEF

0.36 ± 0.10

0.34 ± 0.12

0.069*

0.36 ± 0.10

0.34 ± 0.12

0.077*

  1. Data are presented as mean ± standard deviation; *, Mann-Whitney test; K40–70 = (CT40 − keV- CT70 − keV)/30; K40–100 = (CT40 − keV- CT100 − keV)/60; Zeff, effective atomic number; (N)IC, (normalized) iodine concentration; WC, water concentration; ECV(%)=(1-hematocrit)×NIC; (N)AEF, (normalized) arterial enhancement fraction
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