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Table 1 Characteristics of study patients

From: Prognostic value of metabolic tumor volume on [18F]FDG PET/CT in addition to the TNM classification system of locally advanced non-small cell lung cancer

Variable

All patients

Clinical cohort

Trial cohort

p value

Patients, n (%)

235 (100)

50 (21.3)

185 (78.7)

 

Age, mean (±SD)

66.1 (±8.5)

67.6 (±8.8)

65.7 (±8.4)

.266a

Gender, n (%)

   

.356b

 Female

62 (26.4)

14 (28.0)

48 (25.9)

 

 Male

173 (73.6)

36 (72.0)

137 (74.1)

 

Histology, n (%)

   

< .001b

 SCC

124 (52.8)

17 (34.0)

107 (57.8)

 

 AC

76 (32.3)

21 (42.0)

55 (29.8)

 

 NOS/ others

35 (14.9)

12 (24.0)

23 (12.4)

 

Treatment, n (%)

   

< .001b

 Chemoradiotherapy

211 (89.8)

26 (52.0)

185 (100)

 

 Surgery

24 (10.2)

24 (48.0)

  

UICC stage (8thedition), n (%)

   

< .001b

 IIIa

67 (28.5)

23 (46.0)

44 (23.8)

 

 IIIb

113 (48.1)

22 (44.0)

91 (49.2)

 

 IIIc

55 (23.4)

5 (10.0)

50 (27.0)

 

PET parameter, median (IQR)

 MTV

73.3 (29 - 129)

64.9 (21 - 96)

76.4 (33 - 135)

< .001c

 TLG

385.1 (136 - 716)

276.3 (107 - 601)

414.9 (162 - 832)

< .001c

 SULpeak

10.0 (7 - 13)

9.0 (7 - 11)

10.2 (8 - 13)

< .001c

 SUVmax

15.8 (12 - 20)

14.6 (12 - 17)

16.8 (13 - 20)

.004c

n° of lesions, median (IQR)

2 (1 - 4)

3 (1 - 5)

2 (1 - 4)

0.204a

  1. n counts, SD Standard deviation, SCC Squamous cell carcinoma, AC Adenocarcinoma, NOS Not otherwise specified, IQR Interquartile range, MTV Metabolic tumor volume, TLG Total lesion glycolysis, SUL Standardized uptake value corrected for lean body mass, SUV Standardized uptake value, number
  2. aMann-Whitney U-test
  3. bChi-squared-test
  4. ct-test