Table 3 Multivariable Cox proportional Hazards Regression Analysis for Overall Survival

Cohort^a

1.058

0.612

1.828

0.840

Age

1.022

1.002

1.043

0.031

0.956

0.906

1.008

0.098

1.034

1.011

1.058

0.004

Histology

0.056

0.003

0.441

 AC

reference category

reference category

reference category

 SCC

1.618

1.073

2.439

0.022

8.116

2.320

28.391

0.001

1.328

0.859

2.052

0.201

 NOS/ others

1.628

0.959

2.764

0.071

9.009

2.246

36.141

0.002

1.232

0.67

2.267

0.502

Treatment

 Surgery

reference category

reference category

 Chemoradiotherapy

1.393

0.620

3.131

0.422

1.433

0.618

3.322

0.402

UICC stage

0.003

< 0.001

0.007

 IIIa

reference category

reference category

reference category

 IIIb

1.456

0.948

2.237

0.086

0.909

0.368

2.245

0.836

1.855

1.104

3.116

0.020

 IIIc

2.372

1.432

3.930

< 0.001

13.588

3.349

55.124

< 0.001

2.613

1.457

4.686

0.001

MTV(r)

1.266

1.025

1.562

0.028

1.132

0.618

2.074

0.688

1.211

0.956

1.534

0.112