Table 1 Baseline clinical characteristics of patients
Characteristics | Train cohort(250) | Validation cohort(91) | ||||
|---|---|---|---|---|---|---|
TLS-positive | TLS-negative | P value | TLS-positive | TLS-negative | P value | |
Age (Mean ± SD) | 60.72 ± 10.08 | 62.5 ± 8.11 | 0.135 | 59.57 ± 8.54 | 59.79 ± 9.64 | 0.912 |
Gender n, (%) | 0.386 | 0.547 | ||||
Male | 54 (50) | 80 (56.3) | 12 (40%) | 19 (31.1%) | ||
Female | 54 (50) | 62 (43.7) | 18 (60%) | 42 (68.9%) | ||
Smoke n, (%) | 0.095 | 1 | ||||
Yes | 37 (34.3) | 66 (46.5) | 11 (36.7%) | 22 (36.1%) | ||
No | 71(65.7) | 76 (53.5) | 19 (63.3%) | 39 (63.9%) | ||
TNM stage n, (%) | 0.300 | 0.885 | ||||
IA | 68 (63.0) | 79 (55.6) | 15 (50%) | 33 (54.1%) | ||
IB | 40 (37.0) | 63 (44.4) | 15 (50%) | 28 (45.9%) | ||
TLSs Number (Mean ± SD) | 4.04 ± 2.74 | - | - | 6.1 ± 2.54 | - | - |
TLSs Intra (Mean ± SD) | 1.95 ± 1.68 | - | - | 2.77 ± 2.27 | - | - |
TLSs Peri (Mean ± SD) | 2.07 ± 2.16 | - | - | 3.33 ± 1.77 | - | - |
TLSs Mature (Mean ± SD) | 1.38 ± 1.41 | - | - | 0.93 ± 1.17 | - | - |