Table 2 Relationships between the identified signature and COSMIC curated signatures
Signatures | COSMIC Signature | Related to |
|---|---|---|
S1 | COSMIC Signature 2 | APOBEC |
S2 | COSMIC Signature 13 | APOBEC |
S3 | COSMIC Signature 1 | Spontaneous deamination of 5-methyicytisine |
S4 | COSMIC Signature 18 | Damage by reactive oxygen species |
S5 | COSMIC Signature 22 | Aristolochic acid exposure |
S6 | No similar COSMIC signatures | NA |
S7 | No similar COSMIC signatures | NA |