Table 3 Univariate and multivariate logistic regression analysis of the risk factors of metastatic LNs

Gender

 Female

Reference

—

—

 Male

1.169 (0.751–1.819)

0.489

—

—

Age

0.976 (0.958–0.994)

0.010*

-0.024

0.976 (0.952–1.002)

0.065*

DTC position

 Left lobe

Reference

Reference

 Right lobe

1.803 (1.091–2.981)

0.022*

0.921

2.512 (1.271–4.962)

0.008*

 None

1.216 (0.734–2.014)

0.448

0.271

1.311 (0.672–2.558)

0.427

 Bilateral lobes

2.741 (1.385–5.422)

0.004*

1.315

3.724 (1.504–9.220)

0.004*

DTC foci

 Single

Reference

—

—

 Multiple

2.005 (1.131–3.555)

0.017*

—

—

 None

0.877 (0.567–1.356)

0.555

—

—

AJCC T status

 T1

Reference

 T2

1.560 (0.935–2.601)

0.088

—

—

 T3

3.360 (1.650–6.840)

<0.001

—

—

 T0

1.055 (0.657–1.692)

0.825

—

—

Thyroidectomy

 Partial

Reference

—

—

 Untreated

1.203 (0.629–2.298)

0.577

—

—

 Total

0.895 (0.422–1.898)

0.772

—

—

LN location

 Right neck

Reference

—

—

 Left neck

0.615 (0.418–0.905)

0.014*

—

—

 Middle neck

1.076 (0.281–4.118)

0.915

—

—

LN region

 III + IV + V

Reference

Reference

 VI + VII

1.445 (0.965–2.166)

0.074

0.899

2.458 (1.393–4.337)

0.002*

 I + II

2.561 (0.933–7.034)

0.068

1.779

5.925 (1.347–26.076)

0.019*

Oval shape

 No

Reference

—

—

 Yes

1.037 (0.705–1.527)

0.852

—

—

Hilum absence

 No

Reference

Reference

 Yes

0.247 (0.156–0.392)

< 0.001*

-1.483

0.227 (0.121–0.427)

< 0.001*

Cystic degeneration

 No

Reference

Reference

 Yes

3.881 (1.628–9.253)

0.002*

1.124

3.078 (0.964–9.826)

0.058*

Focal hyperechogenicity

 No

Reference

Reference

 Yes

2.884 (1.858–4.476)

<0.001*

1.307

3.696 (2.021–6.760)

< 0.001*

CDFI

 Hilar

Reference

Reference

 None

1.518 (0.798–2.886)

0.203

0.709

2.031 (0.870–4.741)

0.101

 Mixed

11.715 (5.990–22.914)

<0.001*

2.212

9.138 (4.013–20.808)

< 0.001*

 Peripheral

7.573 (3.642–15.744)

<0.001*

1.786

5.968 (2.388–14.915)

< 0.001*

Microcalcification

 No

Reference

 Yes

1.828 (1.070–3.122)

0.027*

—

—

LN long axis

1.014 (0.981–1.047)

0.418

—

—

LN short axis

1.059 (0.975–1.150)

0.173

-0.190

0.827 (0.732–0.934)

0.002*

Radiomics score

4.759 (3.186–7.108)

< 0.001*

1.510

4.528 (2.564–7.997)

< 0.001*