Fig. 4

Receiver operating characteristic (ROC) curves of above eight pharmacokinetic (PK) histogram parameters. The AUCs of K^trans, K_ep, V_e, and V_p from extend toft model (ETM) were 0.683, 0.688,0.676, and 0.805, respectively. The AUCs of K^trans, K_ep, V_p and F_p from exchange model (ECM) were 0.695, 0.667, 0.843, and 0.776, respectively