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Table 4 Image interpretation and lesion grading of distant metastases

From: The value of whole-body MRI instead of only brain MRI in addition to 18 F-FDG PET/CT in the staging of advanced non-small-cell lung cancer

Patient

  

WB MRI

    

PET

CT

  

Reference standard

Location

 

0

1

2

3

4

0

1

2

3

4

  

1

            

2

            

3

            

4

 

1

    

1

   

benign

liver

4

  

1

       

benign

bone

4

      

1

   

benign

lung

5

   

2

  

1

   

benign

lung

6

  

1

     

1

 

malignant

pleura

6

   

2

     

2

malignant

liver

7

            

8

            

9

            

10

            

11

 

1

        

benign

brain

11

  

1

     

1

 

benign

adrenal

12

   

1

     

2

malignant

bone

12

    

2

     

malignant

brain

13

 

1

    

1

   

benign

liver

13

 

1

      

1

 

malignant

liver

13

    

1

    

1

malignant

adrenal

14

            

15

 

1

1

   

1

   

benign

bone

15

   

1

     

1

malignant

liver

16

    

1

    

1

malignant

bone

16

    

4

     

malignant

brain

17

            

18

            

19

        

1

 

benign

adrenal

20

         

1

benign

lung

21

  

1

       

benign

adrenal

22

    

1

    

1

malignant

bone

23

    

2

    

2

malignant

adrenal

23

    

5

     

malignant

brain

24

  

1

       

benign

liver

25

            

26

 

1

    

1

   

benign

bone

27

 

1

    

1

   

benign

bone

28

            
  1. Abbreviations: WB-MRI, whole-body magnetic resonance imaging; PET/CT, positron emission tomography computed tomography
  2. Number of distant metastases of each grading score in 18F-FDG PET/CT and WB-MRI respectively. Grading of each lesion was performed for WB-MRI and 18F-FDG PET/CT respectively, and interpreted as 1: low suspicion; 2: moderate suspicion; 3: strong suspicion; and 4: definite tumor. Grading score 0: not depicted was not used in the setting of distant metastases evaluation. Lesions scoring 2 points or higher were considered malignant. The reference standard column shows the number of distant metastases according to at least 12 months follow-up data. In patients with distant lesions in more than one location, results are presented in several rows, one for each location. The brain is not included in 18F-FDG PET/CT