Table 2 Multivariable Cox regression analysis for the correlations of significant measurement, patient demographics, cancer staging, and treatment details with outcome

ΔADC%

0.945

(0.910–0.980)

< 0.01

0.887

(0.793–0.991)

0.03

0.923

(0.871–0.978)

< 0.01

Age

1.070

(0.994–1.152)

0.08

0.928

(0.804–1.070)

0.30

1.241

(1.061–1.451)

0.01

Sex

(female as ref.)

1.926

(0.401–9.255)

0.41

2.935

(0.268–32.109)

0.40

5.051

(0.411–62.112)

0.21

T-category

2.458

(0.976–6.187)

0.06

2.887

(0.533–15.632)

0.22

0.923

(0.871–22.164)

0.08

N-category

1.828

(0.0.944–3.538)

0.08

0.757

(0.243–2.355)

0.63

2.447

(0.985–6.077)

0.06

Overall stage

0.168

(0.024–1.193)

0.08

1.644

(0.061–4.585)

0.77

0.560

(0.094–1.525)

0.09

Cycles of IC

0.115

(0.023–0.565)

< 0.01

7.110

(0.304–16.565)

0.22

0.110

(0.055–0.211)

0.01

Cycles of Concurrent chemotherapy

0.771

(0.527–1.129)

0.18

1.708

(0.675–4.324)

0.26

0.459

(0.245–0.858)

0.02