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Table 3 C-index of the RECIST groups and ΔADC% groups for 3- and 5- year DFS, LRRFS, DMFS and OS

From: Change in diffusion weighted imaging after induction chemotherapy outperforms RECIST guideline for long-term outcome prediction in advanced nasopharyngeal carcinoma

 

DFS

LRRFS

DMFS

OS

C-index

(95%CI)

P-value

C-index

(95%CI)

P-value

C-index

(95%CI)

P-value

C-index

(95%CI)

P-value

3-year

        

 RECIST groups

0.47

(0.41–0.52)

Ref.

0.72

(0.60–0.85)

Ref.

0.54

(0.44–0.64)

Ref.

0.45

(0.33–0.58)

Ref.

 ΔADC% groups

0.71

(0.68–0.75)

< 0.01

0.70

(0.66–0.73)

0.89

0.71

(0.67–0.74)

0.13

0.69

(0.63–0.75)

0.29

5-year

        

 RECIST groups

0.51

(0.45–0.58)

Ref.

0.69

(0.56–0.84)

Ref.

0.57

(0.48–0.66)

Ref.

0.53

(0.43–0.64)

Ref.

 ΔADC% groups

0.72

(0.68–0.77)

< 0.01

0.70

(0.68–0.73)

0.78

0.71

(0.68–0.75)

0.22

0.60

(0.52–0.68)

0.68

  1. RECIST groups = responder group vs. non-responder group
  2. ΔADC% groups = ΔADC% < 34.2% group vs. ΔADC% ≥34.2% group
  3. DFS = disease free survival, LRRFS = locoregional recurrence free survival, DMFS = distant metastases free survival, OS = overall survival, ADC = apparent diffusion coefficient