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Table 1 Patient characteristics in the training and validation sets for IASLC grading

From: Differentiating high-grade patterns and predominant subtypes for IASLC grading in invasive pulmonary adenocarcinoma using radiomics and clinical-semantic features

Variables

Training set (n = 370)

Validation set (n = 159)

 

IASLC 1

IASLC 2

IASLC 3

P value

IASLC 1

IASLC 2

IASLC 3

P value

Age (years)

56.512 ± 9.02

58.877 ± 8.878

60.521 ± 9.806

0.017

56.933 ± 10.826

57.543 ± 8.831

58.939 ± 8.119

0.716

Gender

   

0.046

   

0.288

 Male

22

51

127

 

6

13

41

 

 Female

19

63

88

 

9

33

57

 

Diameter (cm)

1.82 ± 0.697

1.864 ± 0.973

2.445 ± 1.102

\(\:<\)0.001

1.377 ± 0.365

1.792 ± 0.922

2.368 ± 0.991

\(\:<\)0.001

Types

   

\(\:<\)0.001

   

\(\:<\)0.001

 Solid

3

85

187

 

1

30

80

 

 Subsolid

38

29

28

 

14

16

18

 

Nodule location

   

0.035

   

0.051

 Peripheral

41

110

196

 

15

46

89

 

 Central

0

4

19

 

0

0

9

 

Shape

   

0.179

   

0.002

 Irregular

18

35

63

 

11

16

27

 

 Regular

23

79

152

 

4

30

71

 

Lobulation

   

0.343

   

0.001

 No

16

40

63

 

12

15

30

 

 Yes

25

74

152

 

3

31

68

 

Spiculation

   

0.001

   

\(\:<\)0.001

 No

26

59

77

 

13

24

29

 

 Yes

15

55

138

 

2

22

69

 

Cavitation

   

0.088

   

0.231

 No

41

108

196

 

15

40

91

 

 Yes

0

6

19

 

0

6

7

 

Vacuole

   

0.017

   

0.162

 No

33

101

162

 

11

42

79

 

 Yes

8

13

53

 

4

4

19

 

Air bronchograms

   

0.003

   

0.048

 No

39

79

152

 

14

40

71

 

 Yes

2

35

63

 

1

6

27

 

Pleural traction

   

0.004

   

0.010

 No

18

49

57

 

9

17

23

 

 Yes

23

65

158

 

6

29

75

 

Vascular convergence

   

0.357

   

0.926

 No

14

53

98

 

7

20

46

 

 Yes

27

61

117

 

8

26

52

 

Obstructive pneumonia

   

0.001

   

0.018

 No

41

109

184

 

15

46

86

 

 Yes

0

5

31

 

0

0

12

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