Variables | Training set (n = 370) | Validation set (n = 159) | ||||||
---|---|---|---|---|---|---|---|---|
 | IASLC 1 | IASLC 2 | IASLC 3 | P value | IASLC 1 | IASLC 2 | IASLC 3 | P value |
Age (years) | 56.512 ± 9.02 | 58.877 ± 8.878 | 60.521 ± 9.806 | 0.017 | 56.933 ± 10.826 | 57.543 ± 8.831 | 58.939 ± 8.119 | 0.716 |
Gender | Â | Â | Â | 0.046 | Â | Â | Â | 0.288 |
 Male | 22 | 51 | 127 |  | 6 | 13 | 41 |  |
 Female | 19 | 63 | 88 |  | 9 | 33 | 57 |  |
Diameter (cm) | 1.82 ± 0.697 | 1.864 ± 0.973 | 2.445 ± 1.102 | \(\:<\)0.001 | 1.377 ± 0.365 | 1.792 ± 0.922 | 2.368 ± 0.991 | \(\:<\)0.001 |
Types | Â | Â | Â | \(\:<\)0.001 | Â | Â | Â | \(\:<\)0.001 |
 Solid | 3 | 85 | 187 |  | 1 | 30 | 80 |  |
 Subsolid | 38 | 29 | 28 |  | 14 | 16 | 18 |  |
Nodule location | Â | Â | Â | 0.035 | Â | Â | Â | 0.051 |
 Peripheral | 41 | 110 | 196 |  | 15 | 46 | 89 |  |
 Central | 0 | 4 | 19 |  | 0 | 0 | 9 |  |
Shape | Â | Â | Â | 0.179 | Â | Â | Â | 0.002 |
 Irregular | 18 | 35 | 63 |  | 11 | 16 | 27 |  |
 Regular | 23 | 79 | 152 |  | 4 | 30 | 71 |  |
Lobulation | Â | Â | Â | 0.343 | Â | Â | Â | 0.001 |
 No | 16 | 40 | 63 |  | 12 | 15 | 30 |  |
 Yes | 25 | 74 | 152 |  | 3 | 31 | 68 |  |
Spiculation | Â | Â | Â | 0.001 | Â | Â | Â | \(\:<\)0.001 |
 No | 26 | 59 | 77 |  | 13 | 24 | 29 |  |
 Yes | 15 | 55 | 138 |  | 2 | 22 | 69 |  |
Cavitation | Â | Â | Â | 0.088 | Â | Â | Â | 0.231 |
 No | 41 | 108 | 196 |  | 15 | 40 | 91 |  |
 Yes | 0 | 6 | 19 |  | 0 | 6 | 7 |  |
Vacuole | Â | Â | Â | 0.017 | Â | Â | Â | 0.162 |
 No | 33 | 101 | 162 |  | 11 | 42 | 79 |  |
 Yes | 8 | 13 | 53 |  | 4 | 4 | 19 |  |
Air bronchograms | Â | Â | Â | 0.003 | Â | Â | Â | 0.048 |
 No | 39 | 79 | 152 |  | 14 | 40 | 71 |  |
 Yes | 2 | 35 | 63 |  | 1 | 6 | 27 |  |
Pleural traction | Â | Â | Â | 0.004 | Â | Â | Â | 0.010 |
 No | 18 | 49 | 57 |  | 9 | 17 | 23 |  |
 Yes | 23 | 65 | 158 |  | 6 | 29 | 75 |  |
Vascular convergence | Â | Â | Â | 0.357 | Â | Â | Â | 0.926 |
 No | 14 | 53 | 98 |  | 7 | 20 | 46 |  |
 Yes | 27 | 61 | 117 |  | 8 | 26 | 52 |  |
Obstructive pneumonia | Â | Â | Â | 0.001 | Â | Â | Â | 0.018 |
 No | 41 | 109 | 184 |  | 15 | 46 | 86 |  |
 Yes | 0 | 5 | 31 |  | 0 | 0 | 12 |  |