Fig. 2

CT values were measured in the ccRCC and aorta of typical case diagram. Placement of regions of interest in the aorta (red circle) and ccRCC (blue circle) avoiding stair-step artefacts and partial volume averaging artefacts by excluding lesion borders. (A) A 45-year-old male, pathologically confirmed as a low-grade (ISUP 1) ccRCC of the right kidney exhibited an ECV of 30.68%; (B) A 53-year-old female, pathologically confirmed as a low-grade (ISUP 2) ccRCC of the left kidney exhibited an ECV of 35.34%; (C) A 61-year-old male, pathologically confirmed as a high-grade (ISUP 3) ccRCC of the left kidney exhibited an ECV of 41.71%; (D) A 73-year-old male, pathologically confirmed as a high-grade (ISUP 4) ccRCC of the left kidney exhibited an ECV of 56.44%. Notes: (A1, B1, C1, D1) unenhanced phase images, (A2, B2, C2, D2) corticomedullary phase (MP) images, (A3, B3, C3, D3) nephrographic phase (NP) images, (A4, B4, C4, D4) delayed phase (DP) images, (A5, B5, C5, D5) Hematoxylin-Eosin staining magnified images (×200), and (A6, B6, C6, D6) Carbonic Anhydrase IX (CAIX) immunohistochemical staining images(×200)