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Table 2 Between-group comparisons of CSF, tumor, and PTBE volumes; DTI-ALPS index

From: Glymphatic system dysfunction and cerebrospinal fluid retention in gliomas: evidence from perivascular space diffusion and volumetric analysis

Groups

DTI-ALPS

P

CSF volume (cm3)

P

Tumor volume (cm3)

P

PTBE volume (cm3)

P

  

< 0.001

 

< 0.001

 

/

 

/

Glioma

1.266 ± 0.258

 

174.53 ± 34.89

 

29.77(36.79)

 

37.48(65.11)

 

Health control

1.395 ± 0.174

 

154.25 ± 20.89

 

/

 

/

 
  

0.013

 

0.394

 

< 0.001

 

< 0.001

LGG

1.345 ± 0.261

 

178.28 ± 32.25

 

11.76(33.03)

 

15.00(27.39)

 

HGG

1.222 ± 0.246

 

172.48 ± 36.30

 

32.89(37.94)

 

49.98(63.75)

 
  

0.594

 

0.658

 

0.800

 

0.411

IDH-WT

1.261 ± 0.252

 

176.66 ± 37.75

 

27.59(32.42)

 

30.62(51.38)

 

IDH-MUT

1.290 ± 0.289

 

173.23 ± 31.72

 

30.62(39.42)

 

24.86(86.97)

 
  

0.017

 

0.597

 

0.004

 

0.054

astrocytoma

1.333 ± 0.286

a0.024

172.44 ± 33.55

 

22.24(41.65)

a0.043

19.74(50.28)

 

oligodendroglioma

1.378 ± 0.242

b0.017

168.30 ± 34.17

 

17.76(22.85)

b0.002

31.73(91.43)

 

glioblastoma

1.204 ± 0.220

c0.563

178.15 ± 37.77

 

35.14(33.98)

c0.873

43.79(53.01)

 
  1. Bold text indicates statistical significance. a glioblastoma vs. oligodendroglioma, b glioblastoma vs. astrocytoma, c oligodendroglioma vs. astrocytoma; LGG, low-grade glioma; HGG, high-grade glioma; DTI-ALPS, the Diffusion Tensor Imaging analysis along the perivascular space; PTBE, peritumoral brain edema; IDH, isocitrate dehydrogenase; WT, wild type; MUT, mutation