Fig. 5

Representative PET/CT images of patients in the different BMI groups with large and sub-centimeter lesions, reconstructed with OSEM and DPL. a-d: PET/CT images of an underweight female patient with cervical cancer (BMI: 16.30) and larger lesions. The arrow indicates a metastatic lymph node in the retroperitoneum with a maximum diameter of 2.63 cm. m-p: PET/CT images of an underweight female patient with lung cancer (BMI:16.18) and sub-centimeter lesions. The arrow indicates a metastatic lymph node in the left hilum with a maximum diameter of 0.58 cm. e-h: PET/CT images of a normal-weight male patient with lung cancer (BMI: 21.23) and larger lesions. The arrow indicates a mass in the left lower lobe with a maximum diameter of 3.88 cm. q-t: PET/CT images of a normal-weight female patient with lymphoma (BMI: 23.73) and sub-centimeter lesions. The arrow indicates a lymph node in the left neck with a maximum diameter of 0.51 cm. i-l: PET/CT images of an overweight female patient with malignant melanoma (BMI: 25.39) and larger lesions. The arrow indicates a metastatic lymph node in the left subclavian region with a maximum diameter of 1.62 cm. u-x: PET/CT images of an overweight male patient with liver cancer (BMI: 28.23) and small lesions. The arrow indicates a metastatic lesion with a maximum diameter of 0.88 cm. Columns 1 and 3 display the fused PET/CT images of patients in the transverse plane, while columns 2 and 4 present the MIPs of the patients’ PET scans. Rows 1, 3 and 5 are the OSEM, Rows 2, 4 and 6 are DPL