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  1. Understanding the impact of epilepsy on pediatric brain tumors is crucial to diagnostic precision and optimal treatment selection. This study investigated MRI radiomics features, tumor location, voxel-based mo...

    Authors: Min-Lan Tsai, Kevin Li-Chun Hsieh, Yen-Lin Liu, Yi-Shan Yang, Hsi Chang, Tai-Tong Wong and Syu-Jyun Peng
    Citation: Cancer Imaging 2025 25:63
  2. According to the updated classification system, human epidermal growth factor receptor 2 (HER2) expression statuses are divided into the following three groups: HER2-over-expression, HER2-low-expression, and H...

    Authors: Xuefeng Hou, Kun Chen, Huiwen Luo, Wengui Xu and Xiaofeng Li
    Citation: Cancer Imaging 2025 25:62
  3. Phyllodes tumors (PTs) are rare breast tumors with high recurrence rates, current methods relying on post-resection pathology often delay detection and require further surgery. We propose a deep-learning-based...

    Authors: Yuqi Yan, Yuanzhen Liu, Yao Wang, Tian Jiang, Jiayu Xie, Yahan Zhou, Xin Liu, Meiying Yan, Qiuqing Zheng, Haifei Xu, Jinxiao Chen, Lin Sui, Chen Chen, RongRong Ru, Kai Wang, Anli Zhao…
    Citation: Cancer Imaging 2025 25:61
  4. To evaluate the effectiveness of a simple positioning aid device in neck CT scans for the diagnosis of thyroid cancer, with a focus on its influence on image quality and diagnostic accuracy.

    Authors: Wei-Hua Lin, Hui-Juan Huang, Wen-Cong Yang, Qing-Wen Huang, Rui-Gang Huang, Fu-Rong Luo, Dong-Yi Chen, Zheng-Han Yang, Hai-Tao Li, Hui-Huang Zeng and Hui-Jun Xiao
    Citation: Cancer Imaging 2025 25:60
  5. The World Health Organization/International Society of Urological Pathology (WHO/ISUP) grading of clear cell renal cell carcinoma (ccRCC) is crucial for prognosis and treatment planning. This study aims to pre...

    Authors: Zhihui Chen, Hongqing Zhu, Hongmin Shu, Jianbo Zhang, Kangchen Gu and Wenjun Yao
    Citation: Cancer Imaging 2025 25:59
  6. As body mass index (BMI) increases, the quality of 2-deoxy-2-[fluorine-18]fluoro-D-glucose (18F-FDG) positron emission tomography (PET) images reconstructed with ordered subset expectation maximization (OSEM) dec...

    Authors: Zhihao Chen, Hongxing Yang, Ming Qi, Wen Chen, Fei Liu, Shaoli Song and Jianping Zhang
    Citation: Cancer Imaging 2025 25:58
  7. The appropriate ligation level of the inferior mesenteric artery (IMA) in left-sided colorectal cancer (CRC) surgery is debated, with metastasis in No. 253 lymph node (No. 253 LN) being a key determining facto...

    Authors: Hongwei Zhang, Kexin Wang, Shurong Liu, Guowei Chen, Yong Jiang, Yingchao Wu, Xiaocong Pang, Xiaoying Wang, Junling Zhang and Xin Wang
    Citation: Cancer Imaging 2025 25:57
  8. Undifferentiated pleomorphic sarcoma (UPS) is the largest subgroup of soft-tissue sarcomas. It demonstrates post-therapeutic hemosiderin deposition, granulation tissue formation, fibrosis, and calcification. O...

    Authors: Raul F. Valenzuela, Elvis Duran-Sierra, Mathew Antony, Behrang Amini, Sam Lo, Keila E. Torres, Robert S. Benjamin, Jingfei Ma, Ken-Pin Hwang, R. Jason Stafford, Dejka Araujo, Andrew J. Bishop, Ravin Ratan, Wei-Lien Wang, Jossue Espinoza, Pia V. Valenzuela…
    Citation: Cancer Imaging 2025 25:56
  9. The prevalence of prostate cancer (PCa) necessitates advanced diagnostic approaches for detection and lesion characterization. Utilizing two patient cohorts (n = 85), this study analyzes a custom-designed 3D ultr...

    Authors: Spencer R. Moavenzadeh, Derek Y. Chan, Eric S. Adams, Sriram Deivasigamani, Srinath Kotamarti, Mark L. Palmeri, Thomas J. Polascik and Kathryn R. Nightingale
    Citation: Cancer Imaging 2025 25:55
  10. One of the main and effective therapy choices for patients with metastatic castration-resistant prostate cancer (mCRPC) is cabazitaxel (CBZ). Cystitis and hematuria are among the most significant non-hematolog...

    Authors: Ahmed H. Zedan, Jesper S. Gade, Karsten Egbert Arnold Zieger, Mads H. Poulsen, Anja Schmidt Vejlgaard and Filip Lund Hjorth Fredensborg
    Citation: Cancer Imaging 2025 25:54
  11. To investigate the diagnostic value of CE-MATRIX-T1FLAIR and 3D CE-T2FLAIR sequences based on Contrast Enhancement Modulated flip Angle Technique in Refocused Imaging with eXtended echo train (CE-MATRIX) techn...

    Authors: Junhui Yuan, Shaobo Fang, Fan Meng, Yue Wu, Dongqiu Shan, Chunmiao Xu, Renzhi Zhang and Xuejun Chen
    Citation: Cancer Imaging 2025 25:53
  12. Authors: Sebastian Zschaeck, Marina Hajiyianni, Patrick Hausmann, Pavel Nikulin, Emily Kukuk, Christian Furth, Paulina Cegla, Elia Lombardo, Joanna Kazmierska, Adrien Holzgreve, Iosif Strouthos, Carmen Stromberger, Claus Belka, Michael Baumann, Mechthild Krause, Guillaume Landry…
    Citation: Cancer Imaging 2025 25:52

    The original article was published in Cancer Imaging 2025 25:18

  13. Gliomas may impair glymphatic function and alter cerebrospinal fluid (CSF) dynamics through structural brain changes, potentially affecting peritumoral brain edema (PTBE) and fluid clearance. This study invest...

    Authors: Weiqiang Liang, Wenbo Sun, Chunyan Li, Jie Zhou, Changyou Long, Huan Li, Dan Xu and Haibo Xu
    Citation: Cancer Imaging 2025 25:51
  14. To explore the potential of using the extracellular volume fraction (ECV), measured through enhanced computed tomography (CT), as a tool for determining the pathological grade of clear cell renal cell carcinom...

    Authors: Jian Liu, Xunlan Zhang, Rui Lv, Xiaoyong Zhang, Rongpin Wang and Xianchun Zeng
    Citation: Cancer Imaging 2025 25:49
  15. Accurate preoperative staging of gastric cancer (GC) depends on effective diagnostic methods. Enhanced computed tomography (enhanced-CT) is a widely used and reliable preoperative assessment tool for GC, Doubl...

    Authors: MingYue Lv, Xu Hui, Xin Yang, SuSu Li, ZhiGuo Mao, XinHua Zhang and KeHu Yang
    Citation: Cancer Imaging 2025 25:48
  16. This study evaluates the impact of deep learning-enhanced T1-weighted VIBE sequences (DL-VIBE) on image quality and procedural parameters during MR-guided thermoablation of liver malignancies, compared to stan...

    Authors: Moritz T. Winkelmann, Jens Kübler, Sebastian Gassenmaier, Dominik M. Nickel, Antonia Ashkar, Konstantin Nikolaou, Saif Afat and Rüdiger Hoffmann
    Citation: Cancer Imaging 2025 25:47
  17. To develop a diagnostic model for predicting the early recurrence of microvascular invasion (MVI)-negative hepatocellular carcinoma (HCC) after surgical resection, using the Liver Imaging Reporting and Data Sy...

    Authors: Yingying Liang, Xiaorui Han, Tingwen Zhou, Chuyin Xiao, Changzheng Shi, Xinhua Wei and Hongzhen Wu
    Citation: Cancer Imaging 2025 25:46
  18. To assess the prognosis predictive value of semi-quantitative metabolic parameters and tumoral metabolic activity based on 123I-meta-iodobenzylguanidine (MIBG) SPECT/CT in pretreatment neuroblastoma (NB) patients...

    Authors: Ziang Zhou, Xu Yang, Guanyun Wang, Xiaoya Wang, Jun Liu, Yanfeng Xu, Kan Ying, Wei Wang and Jigang Yang
    Citation: Cancer Imaging 2025 25:45
  19. To perform a systematic review and meta-analysis that assesses the diagnostic performance of deep learning algorithms applied to breast MRI for predicting axillary lymph nodes metastases in patients of breast ...

    Authors: Chia-Fen Lee, Joseph Lin, Yu-Len Huang, Shou-Tung Chen, Chen-Te Chou, Dar-Ren Chen and Wen-Pei Wu
    Citation: Cancer Imaging 2025 25:44
  20. In lower-grade gliomas (LrGGs, histological grades 2–3), there exist a minority of high-risk molecular subtypes with malignant transformation potential, associated with unfavorable clinical outcomes and shorte...

    Authors: Xiangli Yang, Wenju Niu, Kai Wu, Guoqiang Yang and Hui Zhang
    Citation: Cancer Imaging 2025 25:43
  21. The International Association for the Study of Lung Cancer (IASLC) grading system for invasive non-mucinous adenocarcinoma (ADC) incorporates high-grade patterns (HGP) and predominant subtypes (PS). Following ...

    Authors: Sunyi Zheng, Jiaxin Liu, Jiping Xie, Wenjia Zhang, Keyi Bian, Jing Liang, Jingxiong Li, Jing Wang, Zhaoxiang Ye, Dongsheng Yue and Xiaonan Cui
    Citation: Cancer Imaging 2025 25:42
  22. While total thyroidectomy with central neck dissection (CND) is standard for medullary thyroid cancer (MTC), performing a lateral neck dissection (LND) depends on locoregional metastatic spread and is usually ...

    Authors: Eline C. Jager, Adrienne H. Brouwers, Madelon J. H. Metman, Dilay Aykan, Lisa H. de Vries, Lutske Lodewijk, Menno R. Vriens, Schelto Kruijff and Thera P. Links
    Citation: Cancer Imaging 2025 25:41
  23. To investigate the feasibility of detecting local recurrent nasopharyngeal carcinoma (rNPC) using unenhanced magnetic resonance images (MRI) and optimize a layered management strategy for follow-up with a deep...

    Authors: Yishu Deng, Yingying Huang, Haijun Wu, Dongxia He, Wenze Qiu, Bingzhong Jing, Xing Lv, Weixiong Xia, Bin Li, Ying Sun, Chaofeng Li, Chuanmiao Xie and Liangru Ke
    Citation: Cancer Imaging 2025 25:39
  24. Accurate identification and evaluation of lymph nodes (LNs) in prostate cancer (PCa) patients is crucial for effective staging but can be time-consuming. We utilized a 3D V-Net model to improve the efficiency ...

    Authors: Zhaonan Sun, Pengsheng Wu, Tongtong Zhao, Ge Gao, Huihui Wang, Xiaodong Zhang and Xiaoying Wang
    Citation: Cancer Imaging 2025 25:37
  25. Hepatocellular carcinoma (HCC) is often diagnosed using gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI). Standardized reporting according to the Liver Imaging Reporting and Data System (LI-RA...

    Authors: Róbert Stollmayer, Selda Güven, Christian Marcel Heidt, Kai Schlamp, Pál Novák Kaposi, Oyunbileg von Stackelberg, Hans-Ulrich Kauczor, Miriam Klauss and Philipp Mayer
    Citation: Cancer Imaging 2025 25:36
  26. To explore the value of intratumoral and peritumoral radiomics in preoperative prediction of anaplastic lymphoma kinase (ALK) mutation status and survival in patients with lung adenocarcinoma.

    Authors: Weiyue Chen, Guihan Lin, Ye Feng, Yongjun Chen, Yanjun Li, Jianbin Li, Weibo Mao, Yang Jing, Chunli Kong, Yumin Hu, Minjiang Chen, Shuiwei Xia, Chenying Lu, Jianfei Tu and Jiansong Ji
    Citation: Cancer Imaging 2025 25:35
  27. Accurate segmentation of pelvic and sacral tumors (PSTs) in multi-sequence magnetic resonance imaging (MRI) is essential for effective treatment and surgical planning.

    Authors: Ping Yin, Weidao Chen, Qianrui Fan, Ruize Yu, Xia Liu, Tao Liu, Dawei Wang and Nan Hong
    Citation: Cancer Imaging 2025 25:34
  28. This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymph...

    Authors: Seyyed Ali Hosseini, Ghasem Hajianfar, Brandon Hall, Stijn Servaes, Pedro Rosa-Neto, Pardis Ghafarian, Habib Zaidi and Mohammad Reza Ay
    Citation: Cancer Imaging 2025 25:33
  29. To investigate change in diffusion weighted imaging (DWI) between pre-treatment (pre-) and after induction chemotherapy (post-IC) for long-term outcome prediction in advanced nasopharyngeal carcinoma (adNPC).

    Authors: Qi Yong H. Ai, Ho Sang Leung, Frankie K.F. Mo, Kaijing Mao, Lun M. Wong, Yannis Yan Liang, Edwin P. Hui, Brigette B.Y. Ma and Ann D. King
    Citation: Cancer Imaging 2025 25:32
  30. Programmed death ligand 1 (PD-L1) expression status, closely related to immunotherapy outcomes, is a reliable biomarker for screening patients who may benefit from immunotherapy. Here, we developed and validat...

    Authors: Lihuan Dai, Jinxue Yin, Xin Xin, Chun Yao, Yongfang Tang, Xiaohong Xia, Yuanlin Chen, Shuying Lai, Guoliang Lu, Jie Huang, Purong Zhang, Jiansheng Li, Xiangguang Chen and Xi Zhong
    Citation: Cancer Imaging 2025 25:31
  31. Non-small cell lung cancer (NSCLC) is a common neoplasm with poor prognosis in advanced stages. The clinical work-up in patients with locally advanced NSCLC mostly includes 18F-fluorodeoxyglucose positron emissio...

    Authors: Hanna Holmstrand, M Lindskog, A Sundin and T Hansen
    Citation: Cancer Imaging 2025 25:30
  32. Despite the increasing interest in abbreviated protocols, we adopted an extended protocol for all prostate MRIs. In this study, we assessed the benefits of an extended prostate MRI protocol, measured by the nu...

    Authors: Fabio Porões, Paraskevi Karampa, Thomas Sartoretti, Hugo Najberg, Johannes M. Froehlich, Carolin Reischauer and Harriet C. Thoeny
    Citation: Cancer Imaging 2025 25:29
  33. In 2020, we introduced the Greater Omentum Imaging-Reporting and Data System (GOI-RADS), a novel classification system related to peritoneal lesions. However, its clinical application remained unvalidated.

    Authors: Zhiguang Chen, Liang Sang, Yuan Cheng, Xuemei Wang, Mutian Lv, Yanjun Liu and ZhiQun Bai
    Citation: Cancer Imaging 2025 25:28
  34. To construct and assess a deep learning (DL) signature that employs computed tomography imaging to predict the expression status of programmed cell death ligand 1 in patients with bladder cancer (BCa).

    Authors: Xiaomeng Han, Jing Guan, Li Guo, Qiyan Jiao, Kexin Wang, Feng Hou, Shunli Liu, Shifeng Yang, Chencui Huang, Wenbin Cong and Hexiang Wang
    Citation: Cancer Imaging 2025 25:27
  35. To evaluate the feasibility and value of dynamic contrast-enhanced MRI (DCE-MRI) quantitative analysis and MRI-based radiomics in predicting the efficacy of microwave ablation (MWA) in lung cancers (LCs).

    Authors: Chen Yang, Fandong Zhu, Jing Yang, Min Wang, Shijun Zhang and Zhenhua Zhao
    Citation: Cancer Imaging 2025 25:26
  36. Imaging genomics is a burgeoning field that seeks to connections between medical imaging and genomic features. It has been widely applied to explore heterogeneity and predict responsiveness and disease progres...

    Authors: Xinyi Gou, Aobo Feng, Caizhen Feng, Jin Cheng and Nan Hong
    Citation: Cancer Imaging 2025 25:24
  37. Pelvic MRI is essential for evaluating local and regional tumor extent in uterine cervical cancer (CC). Tumor microstructure captured by diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC...

    Authors: Njål Lura, Kari S. Wagner-Larsen, Stian Ryste, Kristine Fasmer, David Forsse, Jone Trovik, Mari K. Halle, Bjørn I. Bertelsen, Frank Riemer, Øyvind Salvesen, Kathrine Woie, Camilla Krakstad and Ingfrid S. Haldorsen
    Citation: Cancer Imaging 2025 25:23
  38. To refine the existing CT algorithm to enhance inter-reader agreement and improve the diagnostic performance for clear-cell renal cell carcinoma (ccRCC) in solid renal masses less than 4 cm.

    Authors: Pengfei Jin, Linghui Zhang, Hong Yang, Tingting Jiang, Chenyang Xu, Jiehui Huang, Zhongyu Zhang, Lei Shi and Xu Wang
    Citation: Cancer Imaging 2025 25:22
  39. 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. It has shown significant tumor uptake and high sensitivity in lesion detection across a range o....

    Authors: Tengfei Li, Jintao Zhang, Yuanzhuo Yan, Yue Zhang, Wenjie Pei, Qingchu Hua and Yue Chen
    Citation: Cancer Imaging 2025 25:21
  40. Exploring the construction of a fusion model that combines radiomics and deep learning (DL) features is of great significance for the precise preoperative diagnosis of meningioma sinus invasion.

    Authors: Yuan Gui, Wei Hu, Jialiang Ren, Fuqiang Tang, Limei Wang, Fang Zhang and Jing Zhang
    Citation: Cancer Imaging 2025 25:20
  41. This study aims to introduce the concept of habitat subregions and construct an accurate prediction model by analyzing refined medical images, to predict lymph node metastasis (LNM) in patients with intrahepat...

    Authors: Pengyu Chen, Zhenwei Yang, Peigang Ning, Hao Yuan, Zuochao Qi, Qingshan Li, Bo Meng, Xianzhou Zhang and Haibo Yu
    Citation: Cancer Imaging 2025 25:19
  42. Oropharyngeal carcinomas are characterized by an increasing incidence and a relatively good prognosis. Nonetheless, a considerable number of patients develops metachronous distant metastases; identification of...

    Authors: Sebastian Zschaeck, Marina Hajiyianni, Patrick Hausmann, Pavel Nikulin, Emily Kukuk, Christian Furth, Paulina Cegla, Elia Lombardo, Joanna Kazmierska, Adrien Holzgreve, Iosif Strouthos, Carmen Stromberger, Claus Belka, Michael Baumann, Mechthild Krause, Guillaume Landry…
    Citation: Cancer Imaging 2025 25:18

    The Correction to this article has been published in Cancer Imaging 2025 25:52

  43. Accurately predicting the malignant risk of ground-glass nodules (GGOs) is crucial for precise treatment planning. This study aims to utilize convolutional neural networks based on dual-time-point 18F-FDG PET/CT ...

    Authors: Yuhang Liu, Jian Wang, Bulin Du, Yaming Li and Xuena Li
    Citation: Cancer Imaging 2025 25:17
  44. Vesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric MRI (mp-MRI) demonstrated excellent performance in diagnosing muscle-invasive bladder cancer (MIBC) in cases of pure urothelial carc...

    Authors: Peikun Liu, Lingkai Cai, Hongliang Que, Meihua Jiang, Xuping Jiang, Bo Liang, Gongcheng Wang, Linjing Jiang, Xiao Yang and Qiang Lu
    Citation: Cancer Imaging 2025 25:15
  45. Immunotherapy has revolutionized the treatment landscape for head and neck squamous cell carcinoma (HNSCC) and PD-L1 combined positivity score (CPS) scoring is recommended as a biomarker for immunotherapy. The...

    Authors: Cong Ding, Yue Kang, Fan Bai, Genji Bai and Junfang Xian
    Citation: Cancer Imaging 2025 25:14

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